We design and develop novel, efficient synthetic routes tailored to your specific intermediate, bypassing traditional bottlenecks and accelerating your timeline.
Our expertise ensures seamless transition from lab-scale synthesis to robust commercial manufacturing, guaranteeing a consistent and high-quality supply for your project.
We excel in catalytic Hydrogenation, employing tailored catalysts and conditions for selective reductions under both high and low-pressure regimes. For handling highly reactive or thermally sensitive species, our Cryogenic Reaction capabilities allow for precise temperature control down to -78°C and below. Our proficiency in Organometallic Chemistry is key to constructing sophisticated carbon-carbon and carbon-heteroatom bonds, utilizing a range of organolithium, Grignard, and transition metal catalysts. Furthermore, we execute precise Halogenation (Chlorination, Bromination, Fluorination) and other functional group transformations, providing crucial handles for further molecular elaboration.
Our process chemists focus on developing robust, scalable, and cost-effective routes. From milligram-scale feasibility studies to multi-kilogram GMP production, we ensure a seamless transition, delivering intermediates of the highest purity to accelerate your development timeline.
Our service is ideal for overcoming specific synthesis bottlenecks. We excel in projects requiring novel, patented, or complex intermediates not available off-the-shelf. This includes scaling up challenging reactions, developing a more efficient route for cost reduction, or synthesizing a unique building block to accelerate your R&D. We partner with you to de-risk and optimize the pathway to your target molecule.
Our co-development process is collaborative and milestone-driven. It begins with a technical deep-dive to define the target and route. The development phase includes lab-scale synthesis, optimization, and analytical validation. A typical timeline for a new intermediate ranges from 12 to 24 weeks, depending on complexity, from initial inquiry to delivery of first samples. We provide transparent communication at every stage to align with your project schedule.
Quality is integral to our process. We employ state-of-the-art analytical equipment (HPLC, GC, NMR, LC-MS) for rigorous in-process and release testing against agreed specifications. All materials are supported by a comprehensive Certificate of Analysis (CoA). For advanced projects, we offer cGMP-compliant synthesis and full regulatory support documentation (IMP Dossier, DMF) to streamline your filing.
B608, #25 Shenbin Rd, Minhang District, Shanghai, China
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