Shanghai Yunsong Chemical Co., Ltd.
Shanghai Yunsong Chemical Co., Ltd.
  • Iodides
  • Iodides

Iodides

Iodides are highly valued organic intermediates characterized by the iodine atom, which serves as an excellent leaving group. This property makes them exceptionally reactive and versatile electrophiles in key cross-coupling reactions, such as Negishi, Stille, and Suzuki-Miyaura couplings, often under milder conditions. We provide a diverse portfolio of aryl, heteroaryl, and alkyl iodides with guaranteed high purity and stability. Our products are essential for constructing complex molecular architectures in pharmaceutical discovery, agrochemical development, and advanced material science. Custom synthesis is available to meet your specific structural and scalability requirements.

Specification of Iodides

NameCAS NumberMolecular FormulaChemical Structure
Iodobenzene591-50-4C6H5IIodobenzene
4-Iodotoluene (p-Iodotoluene)
624-31-7C7H7I4-Iodotoluene (p-Iodotoluene)
2-Iodotoluene (o-Iodotoluene)
615-37-2C7H7I2-Iodotoluene (o-Iodotoluene)
Methyl Iodide (Iodomethane)
74-88-4CH3IMethyl Iodide (Iodomethane)
Iodocyclohexane (Cyclohexyl iodide)
626-62-0C6H11IIodocyclohexane (Cyclohexyl iodide)



Iodides Mechanism of Action

Iodides are highly effective electrophiles in cross-coupling reactions due to the relatively weak carbon-iodine (C-I) bond, which facilitates oxidative addition with palladium catalysts. This key step occurs readily, often under mild conditions, making iodides superior coupling partners in reactions like Suzuki, Negishi, and Stille. Their high reactivity enables the efficient formation of new carbon-carbon bonds, allowing chemists to construct complex molecular architectures—such as biaryls and functionalized aromatic systems—with excellent yields and selectivity. This makes aryl and heteroaryl iodides indispensable building blocks in pharmaceutical synthesis, material science, and agrochemical development.


Iodides Are Key Precursors

01

Iodides

Iodides are crucial intermediates for synthesizing anticancer drugs, particularly kinase inhibitors and targeted therapies. Their high reactivity in cross-coupling reactions enables the precise construction of complex aromatic and heterocyclic scaffolds essential for drug activity.

02

Iodides

Iodides serve as key building blocks for central nervous system (CNS) pharmaceuticals, including antipsychotics and antidepressants. The iodine atom facilitates efficient carbon-carbon bond formation, allowing for the modular assembly of diverse neuroactive molecular structures.

03

Iodides

Iodides are vital precursors in palladium-catalyzed cross-coupling reactions, a foundational technology in modern drug discovery. This versatility makes them indispensable for creating the core structures of a wide range of bioactive molecules, from antivirals to cardiovascular agents.

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